Program Symposium
09.00 - 09.20
Symposium Opening: Officials’ Welcome / Greetings
Federico Sboarina - the Town Mayor, Francesco Cobello - the Managing Director of the General Hospital Board, and Antonio Lupo - Pro-Rettore of Verona University.
Chairperson: Bernardo Dalla Bernardina and Helen Cross
09.20 - 09.40
Introduction:
From Dravet Syndrome to Sodium Channel Encephalopathies
Renzo Guerrini.
09.40 - 10.10
Sodium Channel and Human Disease
Jeffrey Noebels
10.10 - 10.25
Discussion
10.25 - 10.40
Coffee Break
DRAVET SYNDROME AND OTHER SCN1A RELATED EPILEPSIES
Chairperson: Giuliano Avanzini and Jeffrey Noebels
10.40 - 11.10
SCN1A related phenotypes
Ingrid Scheffer
11.10 - 11.40
Beyond the epilepsies in SCN1A diseases
Rima Nabbout
11.40 - 12.00
Discussion
12.00 - 13.30
Lunch
Chairperson: Rima Nabbout and Tiziana Granata
13.30 - 13.50
Mechanisms and models
Massimo Mantegazza
13.50 - 14.10
Scn1a epigenome editing by the CRISPR/Cas9 system restores excitability and firing activity in Dravet inhibitory interneurons
Vania Broccoli
14.10 - 14.55
Where are we with treatment options?
Helen Cross - Renzo Guerrini - Lieven Lagae
14.55 - 15.10
Discussion
15.10 - 15.30
Management of prolonged seizure from prehospital treatment to intensive care unit
Federico Vigevano
15.30 - 15.45
Long-term outcome - Francesca Darra
15.45 - 15.55
Teenagers - Clinical cases - Domenica Battaglia
15.55 - 16.05
Adults - Clinical cases - Francesca Ragona
16.05 - 16.15
Marseille Experience - Pierre Genton
16.15 - 16.30
Discussion
16.30 - 16.45
Coffee Break
16.45 - 17.05
1978-2018: A 40 year retrospective view of Dravet Syndrome
Bernardo Dalla Bernardina and Charlotte Dravet
17.05 - 18.05
Session with contributions on the topic
Coordinators: Michelle Bureau and Gaetano Cantalupo
18.05 - 18.25
Discussion
19.00
Welcome Dinner
Chairperson: Renzo Guerrini and Jeffrey Noebels
09.00 - 09.35
Dravet Syndrome and its mimics
Carla Marini
09.35 - 09.50
Discussion
SCN2A
09.50 - 10.30
Phenotypic spectrum of SCN2A related disorders, treatment options and outcomes in
Epilepsy and Beyond
Markus Wolff
10.30 - 10.45
Discussion
10.45 - 11.00
Coffee Break
11.00 - 11.30
The genetics of SCN2A
Andreas Brunklaus
11.30 - 12.10
Mechanisms and Models
Holger Lerche
12.10 - 12.30
Discussion
12.30 - 14.00
Lunch
SCN8A
Chairperson: Carla Marini and Markus Wolff
14.00 - 14.30
Phenotypic spectrum of SCN8A related disorders, treatment options and outcomes
Elena Gardella
14.30 - 15.00
The Genetics of SCN8A
Rikke Steensbjerre Møller
15.00 - 15.30
Mechanisms and Models
Miriam Meisler
15.30 - 15.45
Discussion
15.45 - 16.00
Coffee Break
16.00 - 16.30
Concluding remarks SCN1A - SCN2A - SCN8A
Bernardo Dalla Bernardina, Charlotte Dravet, Ingrid Scheffer, Renzo Guerrini and
Jeffrey Noebels
16.30 - 17.30
Session with contributions on the topic
Coordinators: Elena Parrini and Nicola Specchio
17.30 - 17.50
Discussion